Lotrimin AF Cream Uses, Side Effects & Warnings (2024)

Generic name: clotrimazole topical [kloe-TRIM-a-zole]
Brand names: Anti-Fungal Liquid, FungiCURE Pump Spray, Lotrimin AF Cream for Ringworm, Lotrimin AF For Her, Lotrimin AF Jock Itch, ... show all 9 brands
Drug class: Topical antifungals

Medically reviewed by Drugs.com on Aug 1, 2023. Written by Cerner Multum.

What is Lotrimin AF Cream?

Lotrimin AF Cream is an antifungal medication that fights infections caused by fungus.

Lotrimin AF Cream (for the skin) is used to treat skin infections such as athlete's foot, jock itch, ringworm, and yeast infections.

Lotrimin AF Cream may also be used for purposes not listed in this medication guide.

Lotrimin AF Cream side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Lotrimin AF Cream may cause serious side effects. Stop using Lotrimin AF Cream and call your doctor at once if you have:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Lotrimin AF Athlete's Foot Cream side effects (more detail)


Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Related/similar drugs

hydrocortisone topical, clotrimazole topical, ketoconazole topical, terbinafine, miconazole topical, Lamisil, Westcort

Before taking this medicine

You should not use Lotrimin AF Cream if you are allergic to it.

Lotrimin AF Cream is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether clotrimazole topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Lotrimin AF Cream?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Lotrimin AF Cream is for use only on the skin.

Wash your hands before and after using Lotrimin AF Cream, unless you are using it to treat a hand infection.

Clean and dry the affected area. Apply a small amount of the cream (usually twice daily) for 2 to 4 weeks.

Do not cover the treated skin area unless your doctor tells you to. Avoid using bandages or dressings that do not allow air circulation. A light cotton-gauze dressing may be used to protect clothing.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine.

Call your doctor if your symptoms get worse, or if your condition does not improve after 4 weeks of treatment.

Store at room temperature away from moisture and heat.

Detailed Lotrimin AF Athlete's Foot Cream dosage information

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of Lotrimin AF Cream is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using clotrimazole topical?

Avoid getting this medication in your eyes, nose, or mouth.

Avoid using other skin medications on the areas you treat with Lotrimin AF Cream unless your doctor tells you to.

Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.

What other drugs will affect Lotrimin AF Cream?

It is not likely that other drugs you take orally or inject will have an effect on topically applied clotrimazole. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Frequently asked questions

  • What are the most common skin conditions? (with photos)

More about Lotrimin AF Athlete's Foot Cream (clotrimazole topical)

  • Compare alternatives
  • Latest FDA alerts (2)
  • Side effects
  • Dosage information
  • During pregnancy
  • Drug class: topical antifungals
  • Breastfeeding

Patient resources

  • Lotrimin advanced reading
  • Lotrimin AF (Clotrimazole Topical) (Advanced Reading)
  • Lotrimin

Other brands

Clotrimazole-3, Mycelex, FungiCURE Pump Spray, Lotrimin AF For Her Athlete's Foot Cream

Professional resources

  • Clotrimazole monograph
  • Clotrimazole Cream (FDA)

Other brands


Other formulations

  • Lotrimin AF Jock Itch

Related treatment guides

  • Tinea Corporis
  • Tinea Pedis
  • Intertrigo

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 6.01.

Lotrimin AF Cream Uses, Side Effects & Warnings (2024)
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